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Symbol Name ID |
Figla
folliculogenesis specific basic helix-loop-helix MGI:1349421 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Streak ovary |
Hypoplasia of the uterus |
Premature ovarian insufficiency |
Primary amenorrhea |
Secondary amenorrhea |
Female infertility |
| Disease(s) Associated with FIGLA | ||||||
| primary ovarian insufficiency 6 |
| Mouse Phenotypes | reproductive system phenotype |
kinked sperm flagellum |
decreased oocyte number |
oligozoospermia |
abnormal male germ cell morphology |
abnormal spermatocyte morphology |
decreased male germ cell number |
increased female germ cell apoptosis |
increased ovary apoptosis |
abnormal sperm motility |
absent primordial ovarian follicles |
abnormal ovarian folliculogenesis |
small ovary |
seminiferous tubule degeneration |
small testis |
abnormal female meiosis |
abnormal female meiosis I arrest |
arrest of male meiosis |
abnormal oogenesis |
female infertility |
male infertility |
impaired fertilization |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Figlatm1Dean/Figlatm1Dean | * | ||||||||||||||||||||||
| Tg(TSPY1-Figla)#Dean/? | |||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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